Oxford Cardiovascular Tissue BioResource

The Cardiovascular Tissue Sampling and Biobanking project has developed standardised techniques for cardiovascular tissue collection, which have now been applied to establish the Oxford Cardiovascular Tissue BioResource.

This resource facilitates research into mechanisms that underlie cardiovascular disease predisposition, in order to accelerate development of novel primary prevention strategies.

Objectives:

  • Establish standards of excellence in cardiovascular tissue and sample collection that can be applied within a broad range of projects with a focus on cardiovascular disease.
  • Apply these techniques to establish the Oxford Cardiovascular Tissue BioResource.
  • Support the investigation of mechanisms underlying cardiovascular disease predisposition through management of this unique tissue biological resource for research teams both within Oxford and in the wider research community.

Biobank Description:

  • Sample Types: Human Umbilical Vein Endothelial Cells (HUVECs), Human Arterial Smooth Muscle Cells (HUASMCs) and Wharton’s Jelly Mesenchymal Cells (WJ-MSCs) .
  • Sample Formats: Cryopreserved Cells and Umbilical Cord Tissue – Paraffin fixed wax blocks and snap frozen formats.
  • Approximately 250 samples have been collected as of August 2016 against a planned 600.
  • Comprehensive Maternal, Fetal and Neonatal Clinical Data set to match samples.

Collaborations:

The Oxford Cardiovascular Tissue BioResource collection, processing and storage is carried out in collaboration with the Oxford Cardiovascular Clinical Research Facility (CCRF), the John Radcliffe Women’s Centre and NHS Blood and Transplant.

Contacts:

Dr Grace Yu

grace.yu@cardiov.ox.ac.uk

Professor Paul Leeson
paul.leeson@cardiov.ox.ac.uk

www.ccrf.ox.ac.uk/research

Volunteering:

All volunteers who donate samples have been specifically invited to take part. However, if you are interested in volunteering for other research studies or want to know more about other volunteers’ experiences click here.