Prof Clare Verrill
The Experimental Pathology subtheme focuses on translational cellular pathology research and is a novel collaboration with the engineering team based at the Big Data Institute. Cellular Pathology (Histopathology) is a discipline involving evaluation of tissue sections under a microscope and was highlighted within the UK Government’s Industrial Life Sciences Strategy (2017) as being ripe for innovation. Much of the workflow is manual and assessment of samples involves parameters which are unchanged for decades. This subtheme aims to bring novel technologies into the workflow, with a particular emphasis on computational pathology; bringing digital reporting into clinical practice and establishing libraries of slide images that are used to build novel artificial intelligence algorithms to improve workflow or enable correlation with molecular changes within tumours. The subtheme also provides core laboratory and biobanking support including: histology, immunohistochemistry, tissue microarray construction, whole slide imaging and image analysis.