Dr David Wedge
Genomics England has sequenced DNA from 20,000 cancers within the NHS. We are analysing the resulting data from colorectal, endometrial and testicular cancers to find out what makes some cancers more aggressive and resistant to treatment. This will enable doctors to personalise treatment to individual patients.
Tumours contain millions of cells, each of which may have a different set of mutations. We are using novel sequencing technologies to look in detail at how individual cells behave within tumours. This will enable us to predict how individual tumours will respond to different treatments.