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Research Theme

Imaging

You are here: Home > Research Themes > Imaging > Sub-theme: Efficient scanning using cardiovascular computed tomography

Sub-theme: Efficient scanning using cardiovascular computed tomography

Cardiac image from computed tomography angiography
Cardiac image from computed tomography angiography

Computed tomography angiography (CTA) is now integrated into the clinical guidelines for ruling out chest pain. However, as the method stands now, it only detects severe disease, and it is a useful method of excluding significant coronary atherosclerosis, i.e. major narrowing of the artery lumen. However, knowing that 50% of heart attacks happen in the presence of non-severe coronary disease, the unmet need is to identify those patients who are at risk for heart attacks, increasing the sensitivity of CTA, allowing its use for risk stratification, the process of analysing a patient’s risk of heart health problems.

In this sub-theme, we are focused on the development of novel methodologies that will allow efficient scanning and particularly we are working towards the development of innovative image analysis applications that would allow risk re-stratification, or re-assessment, of patients undergoing cardiac CTA. We are also focused on the development of algorithms that will allow extraction of information from standard CTA scans, beyond atherosclerotic disease burden, such as information on the patients’ immunometabolic profile, blood flow in the coronaries and other arterial beds, myocardial physiology and others.


Sub-theme leads

Charalambos Antoniades, Keith Channon, Stefan Neubauer
Division of Cardiovascular Medicine, Radcliffe Department of Medicine

Contact: Charalambos.antoniades@cardiov.ox.ac.uk

  • Charalambos Antoniades
    Charalambos Antoniades
  • Keith Channon
  • Stefan Neubauer
    Stefan Neubauer

Imaging Theme

  • Introduction
  • Sub-theme: Cardiac tissue characterisation with MRI
  • Sub-theme: Computer guided endoscopy for precancerous change in the oesophagus
  • Sub-theme: Development of novel MRI measures of tissue health
  • Sub-theme: Economic and policy considerations of novel imaging techniques
  • Sub-theme: Efficient scanning using cardiovascular computed tomography
  • Sub-theme: Hyperpolarized Magnetic Resonance – making clearer pictures
  • Sub-theme: Hyperpolarised Xenon Imaging (HPX)
  • Sub-theme: Improving the diagnostic quality of ultrasound
  • Sub-theme: Quantitative MRI in hepatopancreaticobiliary (HPB) imaging
  • Sub-theme: Standardisation of new cardiac MRI mapping techniques for immediate clinical applications
  • Sub-theme: Modelling the heart-brain-liver axis via multi-organ MRI in UK Biobank
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