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Research Theme

Diabetes and Metabolism

You are here: Home > Research Themes > Diabetes and Metabolism > Diabetes and Metabolism Core Labs

Diabetes and Metabolism Core Labs

Leader: Jeremy Tomlinson

The Oxford BRC provides core support for a dedicated team of scientists who manage and run the Diabetes and Metabolism Theme laboratory. The lab performs a wide range of biochemical and genomic assays for theme investigators as well as supporting human islet isolation and assessment of human islet quality for clinical and research use. We have a dedicated mass spectrometry unit where metabolic tracers (stable-isotope labelled fatty acids and other molecules) used in our human in vivo studies are analysed, and a number of core platforms, including Envision and MSD plate readers an ILab 650 Clinical Chemistry analyser, ABI 7900s and confocal microscopes.


Thomas Clague

Thomas Clague – BRC Diabetes & Metabolism Lab Manager

As the BRC Diabetes & Metabolism Lab Manager, I head up a small core team in OCDEM that perform a wide range of biochemical and genomic assays for theme investigators, as well as supporting human islet isolation and assessment of human islet quality for clinical and research use.


Farah Nematkhah

I started my career as a lab technician at the Wellcome Trust Centre here at Oxford University. I then left briefly in 2017 for a stint in the private sector. After gaining new industry experience, I re-joined the University of Oxford in September 2019. I am now working in the Diabetes and Metabolism Core Labs and my duties include large scale DNA extraction, quantitation, QC and normalisation and Biobanking. I also help the Pancreas and Islet Cell Transplantation group with isolating and preparing the Islet cells for transplantation.


Bridget Bickers

I started working as a BRC Research Assistant in December 2019 and have been busy extracting DNA from blood samples as part of a large study. My role has also included quantitation, quality control and normalisation of the extracted DNA to ensure that it is suitable for downstream use in sequencing.

Diabetes and Metabolism Theme

  • Introduction
  • Sub-Theme: Translational Physiology, Therapeutics and Medical Innovation
  • Sub-Theme: Translational Islet and Metabolic Tissue Biology
  • Sub-Theme: Pancreas and Islet Cell Transplantation
  • Sub-Theme: Service Innovation and Evaluation
  • Clinical Research Unit / Clinical Investigation Unit
  • Diabetes and Metabolism Core Labs
  • Oxford BioResource
  • Patient involvement with the Diabetes and Metabolism theme
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