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News Category: Research News

New trial for blindness rewrites the genetic code

Researchers have started a new gene therapy clinical trial to treat X-linked retinitis pigmentosa (XLRP), the most common cause of blindness in young people. Retinitis pigmentosa is currently untreatable and leads to a slow and irreversible loss of vision. On 16 March 2017, a 29-year-old British man became the first patient with X-linked retinitis pigmentosa … Read more

Hospital tablet computers cut nurse time by up to 30 per cent, study finds

A project to replace bedside paper charts with tablet computers in Oxfordshire’s NHS hospitals reduced the typical time taken to input patients’ vital signs by up to 30%, a study has found. The System for Electronic Notification and Documentation (SEND) was developed by the University of Oxford for recording patient vital signs. A study of … Read more

Public Health Minister Visits Oxford Cancer Hospital ahead of World Cancer Day

Ahead of World Cancer Day on February 4, Public Health Minister Nicola Blackwood highlighted the importance of UK scientific research to beating cancer during a visit to the Churchill Hospital. The Public Health and Innovation Minister saw state-of-the-art clinical trials and facilities for new cancer treatments and patients, both supported by the NIHR Oxford Biomedical … Read more

Industry partnership to deploy digital technology in NHS

Drayson Technologies, Oxford University and Oxford University Hospitals (OUH) NHS Foundation Trust have signed three agreements to collaborate on the development, testing and future commercialisation of three clinically validated digital health products arising from BRC-funded research undertaken by engineers and doctors at Oxford University and OUH. The products are designed to provide significant improvements in … Read more

Antibiotics, not dirty hospitals, the main cause of C. difficile epidemic

Restricting the use of a common antibiotic was more important than a high profile “deep clean” of hospitals in massively reducing UK antibiotic resistant Clostridium difficile (C. diff) cases, a major new study has found. The study concluded that overuse of antibiotics like ciprofloxacin led to the outbreak of severe diarrhoea caused by C. difficile … Read more

Second key step for eye robot trial

A robot has been used to inject a drug into the back of the eye in a world first for the next phase of a landmark clinical trial at Oxford’s John Radcliffe Hospital. Prof Robert MacLaren used the remotely controlled robot to administer a tiny volume of blood dissolving agent tPA under the retina to … Read more

Funding boost for genetics centre

A major University of Oxford genetics research centre that supports Oxford BRC research is to share £118m of new funding. Global medical research funding charity Wellcome has announced funding for The Wellcome Centre for Human Genetics. The aim of the centre is to advance understanding of health and disease, and span fundamental and social sciences, … Read more

Nanopore genetics breakthrough supported by Oxford BRC

Oxford University’s Wellcome Trust Centre for Human Genetics (WTCHG) and the leading genome analytics company Genomics plc has announced the first sequencing and analysis of multiple human genomes using nanopore technology. The announcement, made on Thursday, December 1, at the Oxford Nanopore Community Meeting in New York City, marks a major breakthrough in sequencing technology … Read more

Tower turns blue for diabetes awareness

Churchill Hospital staff lit Oxford’s Magdalen Tower blue and hosted a research open day to spread awareness about diabetes. Staff from The Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) arranged for the iconic landmark to be lit to mark World Diabetes Day on November 14, a first for the city. Each year, buildings around … Read more

Magdalen Tower set to turn blue for World Diabetes Day

Clinicians and researchers are preparing to light Oxford’s Magdalen Tower blue to mark World Diabetes Day – and have invited patients and visitors to then learn more at an open day about the condition at the Churchill Hospital. The tower at Magdalen College in High Street will follow in the footsteps of other landmarks including … Read more

Record high for Oxford University Hospitals research studies

  The number of medical research studies at Oxford University Hospitals NHS Foundation Trust has hit a record high, new figures show. The number of studies active in May 2016 was 1,786, up seven per cent from 1,664 in May 2015. The figures – up 222 per cent from 554 in May 2008 – show … Read more

HIV cure hope thanks to collaboration

Researchers are hopeful of a cure for HIV after treating the first patient with a promising new treatment that could kill all traces of the virus. A partnership sparked by the National Institute for Health Research (NIHR) and supported by the NIHR Oxford Biomedical Research Centre is behind this collaborative UK effort for the new … Read more

How baby’s genes influence birth weight and later life disease

New research finds genetic differences that help to explain why some babies are born bigger or smaller than others. It also reveals how genetic differences provide an important link between an individual’s early growth and their chances of developing conditions such as type 2 diabetes or heart disease in later life. The large-scale study, published … Read more

Monitoring prostate cancer “as effective as surgery”

Active monitoring of prostate cancer is as effective as surgery and radiotherapy, in terms of survival at 10 years, reports the largest study of its kind, funded by the National Institute for Health Research (NIHR). Results published in New England Journal of Medicine today, show that all three treatments result in similar, and very low, … Read more

World first for robot eye operation

Surgeons at Oxford’s John Radcliffe Hospital have performed the world’s first operation inside the eye using a robot. Robert MacLaren, Professor of Ophthalmology assisted by Dr Thomas Edwards, Nuffield Medical Fellow, used the remotely controlled robot to lift a membrane 100th of a millimetre thick from the retina at the back of the right eye … Read more

Unique Oxford study of vascular disease welcomes 10,000th participant

                                                    Peter Casey was the study’s 10,000th patient   The only project of its kind anywhere that studies all acute vascular events, such as strokes and heart attacks, to develop … Read more

Parents back genetics project at one year milestone

  Parents who want to understand the cause of their infant daughter’s immune deficiency are among more than 1,000 people who participated in the first full year of a ground-breaking NHS genetics project in Oxford. Kevin and Corinne Kirk hope a simple blood sample from daughter Evie, two, could help unlock the mysteries of her … Read more

New hope for shock patients in intensive care

Care for critically-ill patients with shock could be improved, it is hoped, after the first successful testing by University of Oxford scientists of a new machine to record oxygen consumption in real time. The new technology has arisen through a collaboration between Professor Peter Robbins in the Department of Physiology, Anatomy and Genetics and Professors … Read more

Students learn about John Radcliffe brain research

Students pursuing a career in science and medicine visited Oxford’s John Radcliffe Hospital in an event supported by the NIHR Oxford Biomedical Research Centre (BRC). A total 24 students aged 16 to 32 attended talks and interactive sessions on BRC-supported research by the University of Oxford on August 4. India’s Rehmat Kang, 17, tried on … Read more

BRC researcher to lead NIHR funding board

An Oxford BRC-supported researcher is to chair a new national NIHR board to assess funding applications. Prof Andrew Farmer will assess applications to the NIHR Health Technology Assessment programme (NIHR-HTA). The NIHR HTA Programme is the biggest of the NIHR research programmes and assesses around 600 research applications every year. Due to the increasing popularity of … Read more